辅酶Q<sub>10</sub>抑制过氧化氢诱导的血小板线粒体功能紊乱

辅酶Q<sub>10</sub>抑制过氧化氢诱导的血小板线粒体功能紊乱

目的探究辅酶Q<sub>10</sub>（CoQ<sub>10</sub>）对过氧化氢（H<sub>2</sub>O<sub>2</sub>）诱导的血小板线粒体功能紊乱的影响并探讨相关机制。方法采集健康志愿者外周静脉血，制备纯化血小板悬液。用100 μmol/L CoQ<sub>10</sub>与纯化血小板在体外共孵育50 min，再与1 mmol/L H<sub>2</sub>O<sub>2</sub>孵育30 min后（实验...

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Bibliographic Details
Main Authors: 施译琳, 杨奥林, 王锐杰, 牙甫礼, 陈彦球, 杨燕
Format: Article
Language:zho
Published: Editorial Office of Journal of Sun Yat-sen University 2022-01-01
Series:Zhongshan Daxue xuebao. Yixue kexue ban
Subjects:
辅酶Q<sub>10</sub>
血小板
线粒体
凋亡
活性氧簇
Online Access:http://xuebaoyx.sysu.edu.cn/zh/article/doi/10.13471/j.cnki.j.sun.yat-sen.univ(med.sci).2022.0109/
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