Water-soluble cellulose acetate attenuates glucose intolerance through GLP-1 and PYY signal upregulation

Abstract Water-soluble cellulose acetate (WSCA), derived from natural cellulose and acetate, can be used as a food additive and deliver acetate to the large intestine. In this study, we investigated the effects of dietary WSCA supplementation on impaired glucose metabolism in db/db mice, a model of...

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Main Authors: Kohei Asaeda, Tomohisa Takagi, Eiki Murakami, Hikaru Hashimoto, Takeshi Yasuda, Mariko KajiwaraーKubota, Takeshi Sugaya, Katsura Mizushima, Yasuki Higashimura, Ohue-Kitano Ryuji, Ikuo Kimura, Ken Inoue, Kazuhiko Uchiyama, Shu Shimamoto, Yuichi Ukawa, Akiko Kohara, Masatake Kudoh, Yuji Naito, Yoshito Itoh
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:npj Science of Food
Online Access:https://doi.org/10.1038/s41538-025-00505-9
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