Spatial transcriptomics of healthy and fibrotic human liver at single-cell resolution

Spatial transcriptomics of healthy and fibrotic human liver at single-cell resolution

Abstract Single-cell RNA sequencing (scRNA-seq) has advanced our understanding of cell types and their heterogeneity within the human liver, but the spatial organization at single-cell resolution has not yet been described. Here we apply multiplexed error robust fluorescent in situ hybridization (ME...

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Bibliographic Details
Main Authors: Brianna R. Watson, Biplab Paul, Raza Ur Rahman, Liat Amir-Zilberstein, Åsa Segerstolpe, Eliana T. Epstein, Shane Murphy, Ludwig Geistlinger, Tyrone Lee, Angela Shih, Jacques Deguine, Ramnik J. Xavier, Jeffrey R. Moffitt, Alan C. Mullen
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-55325-4
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