A stumbling block in pancreatic cancer treatment: drug resistance signaling networks

A stumbling block in pancreatic cancer treatment: drug resistance signaling networks

The primary node molecules in the cell signaling network in cancer tissues are maladjusted and mutated in comparison to normal tissues, which promotes the occurrence and progression of cancer. Pancreatic cancer (PC) is a highly fatal cancer with increasing incidence and low five-year survival rates....

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Bibliographic Details
Main Authors: Jinming Liu, Biao Zhang, Bingqian Huang, Kexin Zhang, Fujia Guo, Zhizhou Wang, Dong Shang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
pancreatic cancer
signaling network
drug resistance
matrix
gemcitabine
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2024.1462808/full
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