Exploring the mechanism of fibrates regulating HIF-1A in the treatment of ischemic stroke based on network pharmacology and molecular docking

Abstract Fibrates can prevent and treat ischemic stroke (IS), the occurrence and development of IS is closely related to hypoxia-inducible factor-1A (HIF-1A). However, the exact mechanism by which fibrates regulate HIF-1A to treat IS remains unclear. So network pharmacology and molecular docking wer...

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Bibliographic Details
Main Authors: Fengjiao Yang, Zixuan Yang, Ya Yan, Yun Gu, Pengyu Wang, Min Wang, Jianjie Chen, Xiaoshan Du, Guangming Wang
Format: Article
Language:English
Published: BMC 2024-12-01
Series:BMC Research Notes
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Online Access:https://doi.org/10.1186/s13104-024-07031-z
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