Leptin Inhibits the Proliferation of Vascular Smooth Muscle Cells Induced by Angiotensin II through Nitric Oxide-Dependent Mechanisms
Objective. This study was designed to investigate whether leptin modifies angiotensin (Ang) II-induced proliferation of aortic vascular smooth muscle cells (VSMCs) from 10-week-old male Wistar and spontaneously hypertensive rats (SHR), and the possible role of nitric oxide (NO). Methods. NO and NO s...
Saved in:
Main Authors: | Amaia Rodríguez, Javier Gómez-Ambrosi, Victoria Catalán, Ana Fortuño, Gema Frühbeck |
---|---|
Format: | Article |
Language: | English |
Published: |
Wiley
2010-01-01
|
Series: | Mediators of Inflammation |
Online Access: | http://dx.doi.org/10.1155/2010/105489 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Degraded products generated by iron stent inhibit the vascular smooth muscle cell proliferation by downregulating AP-1
by: Jiabing Huang, et al.
Published: (2025-01-01) -
Qingxuan Jiangya Decoction Reverses Vascular Remodeling by Inducing Vascular Smooth Muscle Cell Proliferation in Spontaneously Hypertensive Rats
by: Jianfeng CHU, et al.
Published: (2016-06-01) -
Evidence That ADAM17 Mediates the Protective Action of CGRP against Angiotensin II-Induced Inflammation in Vascular Smooth Muscle Cells
by: Si-yu Zeng, et al.
Published: (2018-01-01) -
Biosynthetic Pathways and the Role of the Mas Receptor in the Effects of Angiotensin-(1–7) in Smooth Muscles
by: Marcio Augusto Fressatto de Godoy, et al.
Published: (2012-01-01) -
Adipocytokines in Atherothrombosis: Focus on Platelets and Vascular Smooth Muscle Cells
by: Giovanni Anfossi, et al.
Published: (2010-01-01)