Functions of double‐negative B cells in autoimmune diseases, infections, and cancers

Functions of double‐negative B cells in autoimmune diseases, infections, and cancers

Abstract Most mature B cells can be divided into four subtypes based on the expression of the surface markers IgD and CD27: IgD+CD27− naïve B cells, IgD+CD27+ unswitched memory B cells, IgD−CD27+ switched memory B cells, and IgD−CD27− double‐negative (DN) B cells. Despite their small population size...

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Bibliographic Details
Main Authors: Michael King Yung Chung, Lanqi Gong, Dora Lai‐Wan Kwong, Victor Ho‐Fun Lee, Ann Wing‐Mui Lee, Xin‐Yuan Guan, Ngar‐Woon Kam, Wei Dai
Format: Article
Language:English
Published: Springer Nature 2023-06-01
Series:EMBO Molecular Medicine
Subjects:
autoimmune disease
cancer immunosuppression
COVID‐19
double‐negative B cells
tumor microenvironment
Online Access:https://doi.org/10.15252/emmm.202217341
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https://doi.org/10.15252/emmm.202217341

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