ATRA-induced NEAT1 upregulation promotes autophagy during APL cell granulocytic differentiation.

ATRA-induced NEAT1 upregulation promotes autophagy during APL cell granulocytic differentiation.

<h4>Aims</h4>Acute promyelocytic leukemia (APL) progresses quickly and often leads to early hemorrhagic death. Treatment with all-trans retinoic acid (ATRA) promotes differentiation of APL cells and clinical remission, making APL a potentially curable malignancy. Understanding how ATRA w...

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Bibliographic Details
Main Authors: Doudou Tang, Huihui Wang, Yafeng Jiang, Mingjie Chen, Guangsen Zhang, Shangjie Wu, Yewei Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0316109
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