Comparative effects of raw and processed cistanche glycosides on the HPT axis and gut microbiota in a rat model of kidney-yang deficiency

Comparative effects of raw and processed cistanche glycosides on the HPT axis and gut microbiota in a rat model of kidney-yang deficiency

IntroductionKidney Yang Deficiency (KYD) is a metabolic disorder associated with kidney damage. Its slow progression means that causative factors and effective therapeutic agents remain unclear. Extensive evidence links KYD to gut microbiome metabolic diseases and the Hypothalamic-Pituitary-Thyroid...

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Bibliographic Details
Main Authors: Xiaoqing Shen, Jing Lian, Chao Zhang, Yixiang Miu, Yuan Zhang, Ji Shi, Nan Xu, Tianzhu Jia
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Pharmacology
Subjects:
Cistanche deserticola
feces metabolomics
gut microbiota
total glycosides
HPT axis
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1597564/full
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