CT-based quantification of intratumoral heterogeneity for predicting distant metastasis in retroperitoneal sarcoma

Abstract Objectives Retroperitoneal sarcoma (RPS) is highly heterogeneous, leading to different risks of distant metastasis (DM) among patients with the same clinical stage. This study aims to develop a quantitative method for assessing intratumoral heterogeneity (ITH) using preoperative contrast-en...

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Main Authors: Jun Xu, Jian-guo Miao, Chen-xi Wang, Yu-peng Zhu, Ke Liu, Si-yuan Qin, Hai-song Chen, Ning Lang
Format: Article
Language:English
Published: SpringerOpen 2025-05-01
Series:Insights into Imaging
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Online Access:https://doi.org/10.1186/s13244-025-01977-9
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