Assessment of submicron bone tissue composition in plastic-embedded samples using optical photothermal infrared (O-PTIR) spectral imaging and machine learning

Understanding the composition of bone tissue at the submicron level is crucial to elucidate factors contributing to bone disease and fragility. Here, we introduce a novel approach utilizing optical photothermal infrared (O-PTIR) spectroscopy and imaging coupled with machine learning analysis to asse...

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Bibliographic Details
Main Authors: Isha Dev, Sofia Mehmood, Nancy Pleshko, Iyad Obeid, William Querido
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Journal of Structural Biology: X
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2590152424000163
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