Upregulated miR-10b-5p as a potential miRNA signature in amyotrophic lateral sclerosis patients

Upregulated miR-10b-5p as a potential miRNA signature in amyotrophic lateral sclerosis patients

Amyotrophic lateral sclerosis (ALS) is a fatal, adult-onset disease marked by a progressive degeneration of motor neurons (MNs) present in the spinal cord, brain stem and motor cortex. Death in most patients usually occurs within 2–4 years after symptoms onset. Despite promising progress in delineat...

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Bibliographic Details
Main Authors: Banaja P. Dash, Axel Freischmidt, Anika M. Helferich, Albert C. Ludolph, Peter M Andersen, Jochen H. Weishaupt, Andreas Hermann
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-11-01
Series:Frontiers in Cellular Neuroscience
Subjects:
amyotrophic lateral sclerosis
human induced pluripotent stem cells
motor neurons
microRNA
next generation RNA sequencing
differentially expressed
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2024.1457704/full
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https://www.frontiersin.org/articles/10.3389/fncel.2024.1457704/full

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