Temporal dynamics of the multi-omic response reveals the modulation of macrophage subsets post-myocardial infarction

Temporal dynamics of the multi-omic response reveals the modulation of macrophage subsets post-myocardial infarction

Abstract Aims Macrophage-mediated inflammatory response plays a pivotal role in the pathological process of myocardial infarction (MI). Although single-cell RNA sequencing (scRNA-seq) shed light on the differentiation and function of macrophage subsets post-MI, it failed to capture protein-level cha...

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Bibliographic Details
Main Authors: Yuan Wu, Panting Wei, Bin Li, Jiaqi He, Ting Zhou, Qingbin Hou, Yunhao Yu, Jingjin Hou, Chenghui Yan, Yaling Han
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Journal of Translational Medicine
Subjects:
Myocardial infraction
Proteomics
Transcriptomics
Comparative analysis
Post-translational modifications
Online Access:https://doi.org/10.1186/s12967-025-06726-6
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https://doi.org/10.1186/s12967-025-06726-6

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