Nicotinamide Mononucleotide Alleviates Bile Acid Metabolism and Hormonal Dysregulation in Letrozole-Induced PCOS Mice

Nicotinamide Mononucleotide Alleviates Bile Acid Metabolism and Hormonal Dysregulation in Letrozole-Induced PCOS Mice

Polycystic ovary syndrome (PCOS) involves complex genetic, metabolic, endocrine, and environmental factors. This study explores the effects of nicotinamide mononucleotide (NMN) in a letrozole-induced PCOS mouse model, focusing on metabolic regulation. Letrozole-induced aromatase inhibition elevated...

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Bibliographic Details
Main Authors: Caifang Ren, Shuang Zhang, Jianyu Ma, Junjie Huang, Pan Huang, Mingzi Qu, Haoyue Zhao, Zhengrong Zhou, Aihua Gong
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Biology
Subjects:
PCOS
androgens
bile acids
NMN
metabolomics
Online Access:https://www.mdpi.com/2079-7737/13/12/1028
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