MicroRNA-21-5p from induced pluripotent stem cells promotes neuroprotection of retinal ganglion cells in optic nerve crush model

Abstract Introduction Retinal ganglion cells (RGCs) are susceptible to degenerative conditions such as glaucoma and traumatic optic neuropathies, which lead to vision loss. MicroRNA-21-5p has demonstrated potential neuroprotective effects, but its mechanisms in optic nerve injury remain underexplore...

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Bibliographic Details
Main Authors: Qing Xia, Wei Chen, Jiawei Xiong, Xiaofen Mo
Format: Article
Language:English
Published: BMC 2025-08-01
Series:BMC Ophthalmology
Subjects:
Online Access:https://doi.org/10.1186/s12886-025-04244-z
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