脑小血管病与代谢：危险因素、治疗靶点和未来方向Cerebral Small Vessel Disease and Metabolism: Risk Factors, Therapeutic Targets, and Future Directions
明确脑小血管病（cerebral small vessel disease，CSVD）的代谢危险因素并进行及时、系统的管控至关重要。目前残余代谢危险因素与CSVD的相关性尚存争议，而靶向危险因素治疗CSVD的临床效果尚缺乏循证依据。本文综合分析炎症、肠道菌群紊乱、高同型半胱氨酸血症及高尿酸血症等残余代谢危险因素与CSVD发生、发展的相关性，进一步探讨靶向代谢危险因素的潜在治疗方案，强调代谢组学在CSVD新型代谢生物标志物发现和风险预测模型建立中的重要作用，并展望未来研究方向，为CSVD的早期诊断、机制探索、危险因素管控和多学科综合管理提供理论依据。 Abstract: It is cruci...
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| Format: | Article |
| Language: | zho |
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Editorial Department of Chinese Journal of Stroke
2024-12-01
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| Series: | Zhongguo cuzhong zazhi |
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| Online Access: | https://www.chinastroke.org.cn/CN/10.3969/j.issn.1673-5765.2024.12.005 |
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