In-silico screening of small compounds against Lassa fever haemorrhagic virus nucleoprotein

In-silico screening of small compounds against Lassa fever haemorrhagic virus nucleoprotein

Abstract Lassa fever hemorrhagic virus (LFHV) outbreaks in Nigeria continue to increase. With the possibility of a potentially deadly pandemic and the absence of a vaccine, an effective candidate drug that presents with no adverse effects and better clinical outcomes is urgently needed; hence, the a...

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Main Authors: Ekpo Eyo Antai, Uwem Okon Edet, Elizabeth N. Mbim, Ini Ubi Bassey, Sozan M. Abdelkhalig, Francisca O. Nwaokorie, Ehssan Moglad, Jamda Ponmak, Samia Al-Shouli, Sawsan AlShouli, Destiny E. Charlie, Mohnad Abdalla
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
Subjects:
Lassa fever virus
DFT
Docking
Simulation
Nucleoprotein
Nigeria
Online Access:https://doi.org/10.1038/s41598-025-89989-9
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https://doi.org/10.1038/s41598-025-89989-9

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