Exosomal encapsulation of a steviol derivative SD9 to overcome TRAIL resistance as a highly effective therapy against lung cancer
Abstract Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is a promising pro-apoptotic factor. However, it has showed very limited efficacies due to low bioavailability and common drug resistance in cancers. Extracellular vesicle delivery of TRAIL (EV-T) has significantly improv...
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| Main Authors: | Quanjiang Li, Yufeng Xie, Wanting Zhang, Jun Peng, Zhujie Deng, Rui Tian, Xiubin Kuang, Bin Xie, Chen Huang, Yu Zhao, Zhengqiang Yuan |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-06-01
|
| Series: | Cancer Nanotechnology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12645-025-00329-y |
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