Functional characterization of a novel protein-coding circular RNA, circRNA_1193, from the mAAP gene in silkworm and its role in antiviral defense against BmCPV

Functional characterization of a novel protein-coding circular RNA, circRNA_1193, from the mAAP gene in silkworm and its role in antiviral defense against BmCPV

ABSTRACT A novel circular RNA, circRNA_1193, which originates from the membrane alanyl aminopeptidase-like gene in silkworms, was explored for its potential function and regulatory mechanism. We validated the presence of circRNA_1193 in Bombyx mori cytoplasmic polyhedrosis virus (BmCPV)-infected sil...

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Main Authors: Song Li, Zeen Shen, Hongchuan Zhao, Xialing Chen, Qunnan Qiu, Xinyu Tong, Min Zhu, Xing Zhang, Chengliang Gong, Xiaolong Hu
Format: Article
Language:English
Published: American Society for Microbiology 2025-05-01
Series:mBio
Subjects:
silkworm
BmCPV
circRNA_1193
ORF
virus replication
Online Access:https://journals.asm.org/doi/10.1128/mbio.00125-25
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https://journals.asm.org/doi/10.1128/mbio.00125-25

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