Escherichia coli ribosomal protein S1 unfolds structured mRNAs onto the ribosome for active translation initiation.
Regulation of translation initiation is well appropriate to adapt cell growth in response to stress and environmental changes. Many bacterial mRNAs adopt structures in their 5' untranslated regions that modulate the accessibility of the 30S ribosomal subunit. Structured mRNAs interact with the...
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| Main Authors: | Mélodie Duval, Alexey Korepanov, Olivier Fuchsbauer, Pierre Fechter, Andrea Haller, Attilio Fabbretti, Laurence Choulier, Ronald Micura, Bruno P Klaholz, Pascale Romby, Mathias Springer, Stefano Marzi |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2013-12-01
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| Series: | PLoS Biology |
| Online Access: | https://doi.org/10.1371/journal.pbio.1001731 |
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