Randomised, controlled clinical trial evaluating the effects of preoperative insomnia treatment on postoperative pain control and recovery: a protocol for the Promoting Sleep to Alleviate Pain-Arthroplasty (PROSAP-A) trial

Introduction Sleep is a biological necessity with vital effects on all tissues and organs of the body. Preoperative sleep disturbance is associated with increased postoperative pain intensity and opioid consumption. Given that insomnia is a potentially modifiable risk factor, interventions targeting...

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Main Authors: Martin Kraepelien, Michael R Irwin, Eva Kosek, Michael T Smith, Martin F Bjurström, Kristoffer Bothelius, Pernilla Maathz, Susanna Jernelöv, Alexander H C Rosenström, Andrea Niklasson, Richard Olmstead, Patrick H Finan
Format: Article
Language:English
Published: BMJ Publishing Group 2025-07-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/15/7/e099785.full
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