Oxidative stress promotes lipid-laden macrophage formation via CYP1B1

Oxidative stress promotes lipid-laden macrophage formation via CYP1B1

Emerging evidence suggests that lipid-laden macrophages (LLM) participate in lung damage in various clinical conditions. However, the mechanisms involved in LLM formation are not fully understood. In this study, we aimed to investigate the link between reactive oxygen species (ROS) and LLM formation...

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Bibliographic Details
Main Authors:	Yin Zhu, Saugata Dutta, Yohan Han, Dooyoung Choi, Francesca Polverino, Caroline A. Owen, Payaningal R. Somanath, Xiaoyun Wang, Duo Zhang
Format:	Article
Language:	English
Published:	Elsevier 2025-02-01
Series:	Redox Biology
Subjects:	CYP1B1 COPD Cigarette smoking E-Cigarette Reactive oxygen species Carvedilol
Online Access:	http://www.sciencedirect.com/science/article/pii/S2213231724004592
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