Co-infusion of mesenchymal stromal cells to prevent GVHD after allogeneic hematopoietic cell transplantation from HLA-mismatched unrelated donors after reduced-intensity conditioning: a double-blind randomized study and literature review

Co-infusion of mesenchymal stromal cells to prevent GVHD after allogeneic hematopoietic cell transplantation from HLA-mismatched unrelated donors after reduced-intensity conditioning: a double-blind randomized study and literature review

Abstract Background Mesenchymal stromal cells (MSC) have immunomodulatory and hematopoiesis-supporting properties that could potentially benefit hematopoietic stem cell (HSC) engraftment and decrease the incidence and/or severity of graft-versus-host disease (GVHD). Methods Based on our previous pil...

Full description

Saved in:
Bibliographic Details
Main Authors: Gérôme Lombardo, Chantal Lechanteur, Alexandra Briquet, Laurence Seidel, Evelyne Willems, Sophie Servais, Etienne Baudoux, Tessa Kerre, Pierre Zachee, Julie Herman, Audrey Janssen, Joséphine Muller, Frédéric Baron, Yves Beguin
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Stem Cell Research & Therapy
Subjects:
Allogeneic hematopoietic cell transplantation
Mesenchymal stromal cells
GVHD
Prevention
HLA mismatch
Online Access:https://doi.org/10.1186/s13287-024-04064-w
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1186/s13287-024-04064-w

Similar Items