The emergence of DNAM-1 as the facilitator of NK cell-mediated killing in ovarian cancer

The emergence of DNAM-1 as the facilitator of NK cell-mediated killing in ovarian cancer

IntroductionOvarian cancer (OC) is the sixth most common malignancy in women and the poor 5-year survival emphasises the need for novel therapies. NK cells play an important role in the control of malignant disease but the nature of tumour-infiltrating and peripheral NK cells in OC remains unclear.M...

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Bibliographic Details
Main Authors: Rachel Pounds, Wayne Croft, Hayden Pearce, Tasnia Hossain, Kavita Singh, Janos Balega, David N. Jeevan, Sudha Sundar, Sean Kehoe, Jason Yap, Paul Moss, Jianmin Zuo
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Immunology
Subjects:
HGSOC
NK cells
DNAM-1
cancer immunology
ovarian cancer
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1477781/full
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