When more sugar is better—a GPI side chain modification results in a less virulent phenotype during a protozoan infection

ABSTRACT The assembly and function of side chain modifications of glycosylphosphatidylinositol (GPI) units (anchors or free forms) are poorly defined. In a recent study, two enzymes, PIGJ and PIGE, of the protozoan parasite Toxoplasma gondii were identified and shown to be involved in the assembly o...

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Bibliographic Details
Main Author: Frank Seeber
Format: Article
Language:English
Published: American Society for Microbiology 2024-12-01
Series:mBio
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mbio.02740-24
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