Construction of enterovirus G expressing reporter genes for antiviral drug screening assays

Construction of enterovirus G expressing reporter genes for antiviral drug screening assays

Abstract The emergence of Enterovirus G strains harboring recombinant papain-like protease (EV-G-PLP) poses a significant threat to the global swine health with zoonotic potential. Addressing the critical lack of targeted treatments, we developed a reverse genetics system for the CH/20GXNN/PLP2020 s...

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Bibliographic Details
Main Authors: Kaige Chen, Dalin Hong, Lingyou Zeng, Jinni Bian, Shiting Huang, Yifeng Qin, Yeshi Yin, Weijian Huang, Ying Chen, Zuzhang Wei, Kang Ouyang
Format: Article
Language:English
Published: BMC 2025-08-01
Series:BMC Veterinary Research
Subjects:
Enterovirus G
Infectious clone
Reporter gene
Antiviral drug screening
Online Access:https://doi.org/10.1186/s12917-025-04960-0
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https://doi.org/10.1186/s12917-025-04960-0

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