Hijacking of the nervous system in cancer: mechanism and therapeutic targets

Hijacking of the nervous system in cancer: mechanism and therapeutic targets

Abstract The activity of neurons in the vicinity of tumors is linked to a spectrum of cellular mechanisms, including the facilitation of tumor cell proliferation, synapse formation, angiogenesis, and macrophage polarization. This review consolidates the current understanding of neuro-oncological reg...

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Bibliographic Details
Main Authors: Yu Zhang, Qili Liao, Xuyang Wen, Jiayan Fan, Tifei Yuan, Xuemei Tong, Renbing Jia, Peiwei Chai, Xianqun Fan
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Molecular Cancer
Subjects:
Cancer
Nervous system
Neurotransmitters
Neurotrophic factors
Tumor microenvironment
Therapeutic implications
Online Access:https://doi.org/10.1186/s12943-025-02246-5
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