Detecting global and local hierarchical structures in cell-cell communication using CrossChat

Abstract Cell-cell communication (CCC) occurs across different biological scales, ranging from interactions between large groups of cells to interactions between individual cells, forming a hierarchical structure. Globally, CCC may exist between clusters or only subgroups of a cluster with varying s...

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Bibliographic Details
Main Authors: Xinyi Wang, Axel A. Almet, Qing Nie
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-54821-x
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