Features of clinical manifestations of rheumatoid arthritis in patients after failure of conventional synthetic disease-modifying antirheumatic drugs therapy depending on the signs of central sensitization

Features of clinical manifestations of rheumatoid arthritis in patients after failure of conventional synthetic disease-modifying antirheumatic drugs therapy depending on the signs of central sensitization

Central sensitization (CS) is a condition characterised by (associated with) neuroplastic changes in nociceptive neurons, sub-threshold afferent input, pain hypersensitivity and development widespread pain. Insufficient response to disease-modifying antirheumatic drugs (DMARDs) can be caused by CS.O...

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Main Authors: A. S. Potapova, A. E. Karateev, E. Yu. Polishchuk, E. V. Matyanova, T. S. Panevin, A. S. Semashko, A. O. Bobkova, A. R. Khalmetova, E. S. Filatova, V. N. Amirjanova, A. M. Lila
Format: Article
Language:Russian
Published: IMA PRESS LLC 2023-04-01
Series:Научно-практическая ревматология
Subjects:
rheumatoid arthritis
disease activity
pain
fatigue
central sensitization
Online Access:https://rsp.mediar-press.net/rsp/article/view/3324
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