GENETICS OF SUSCEPTIBILITY TO INFECTIOUS DISEASES

GENETICS OF SUSCEPTIBILITY TO INFECTIOUS DISEASES

Genetic characteristics of host organism may cause susceptibility to a variety of bacteria, viruses and fungi, as well as influence the course of infectious diseases. Multiple studies indicate the existence of alleles predisposing to infections. Furthermore, there are about 300 nosological entities...

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Bibliographic Details
Main Authors: E. N. Suspitsin, E. Yu. Skripchenko, E. N. Imyanitov, N. V. Skripchenko
Format: Article
Language:Russian
Published: Journal Infectology 2017-04-01
Series:Журнал инфектологии
Subjects:
genetic susceptibility
mutation
primary immunodeficiencies
dna diagnostics
infectious diseases
Online Access:https://journal.niidi.ru/jofin/article/view/559
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Summary:Genetic characteristics of host organism may cause susceptibility to a variety of bacteria, viruses and fungi, as well as influence the course of infectious diseases. Multiple studies indicate the existence of alleles predisposing to infections. Furthermore, there are about 300 nosological entities of primary immunodeficiencies (PID), i.e., inherited defects of immunity. Timely diagnosis of such conditions is quite challenging; however, it is vital for improving quality of patient care. Modern methods of DNA analysis allow establishing genetic causes of vulnerability to certain infectious agents in many individuals
ISSN:2072-6732

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