Designing a broad-spectrum multi-epitope subunit vaccine against leptospirosis using immunoinformatics and structural approaches

Designing a broad-spectrum multi-epitope subunit vaccine against leptospirosis using immunoinformatics and structural approaches

IntroductionLeptospirosis, caused by Leptospira interrogans, is a neglected zoonotic disease that poses a significant global health risk to both humans and animals. The rise of antimicrobial resistance and the inefficacy of existing vaccines highlight the urgent need for new preventive strategies.Me...

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Bibliographic Details
Main Authors:	Guneswar Sethi, Young Kyu Kim, Su-Cheol Han, Jeong Ho Hwang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-01-01
Series:	Frontiers in Immunology
Subjects:	leptospirosis multi-epitope subunit vaccine immunoinformatics population coverage molecular docking molecular dynamics simulation
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1503853/full
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