m6A-modified circCacna1c regulates necroptosis and ischemic myocardial injury by inhibiting Hnrnpf entry into the nucleus

m6A-modified circCacna1c regulates necroptosis and ischemic myocardial injury by inhibiting Hnrnpf entry into the nucleus

Abstract Background Circular RNAs (circRNAs) are differentially expressed in various cardiovascular diseases, including myocardial infarction (MI) injury. However, their functional role in necroptosis-induced loss of cardiomyocytes remains unclear. We identified a cardiac necroptosis-associated circ...

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Bibliographic Details
Main Authors: Yi Jia, Xiaosu Yuan, Luxin Feng, Qingling Xu, Xinyu Fang, Dandan Xiao, Qi Li, Yu Wang, Lin Ye, Peiyan Wang, Xiang Ao, Jianxun Wang
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Cellular & Molecular Biology Letters
Subjects:
circCacna1c
Cardiomyocyte necroptosis
Myocardial infarction
N6-methyladenosine
Hnrnpf
Online Access:https://doi.org/10.1186/s11658-024-00649-8
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https://doi.org/10.1186/s11658-024-00649-8

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