The regulation of pyroptosis by post-translational modifications: molecular mechanisms and therapeutic targets
Summary: Pyroptosis, a type of programmed cell death mediated by gasdermin family proteins, releases a large amount of immune stimulatory substances, which further contribute to inflammation and elicit an adaptive immune response against tumours and pathogens. And it occurs through multiple pathways...
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Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2024-11-01
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Series: | EBioMedicine |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2352396424004560 |
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