The regulation of pyroptosis by post-translational modifications: molecular mechanisms and therapeutic targets

Summary: Pyroptosis, a type of programmed cell death mediated by gasdermin family proteins, releases a large amount of immune stimulatory substances, which further contribute to inflammation and elicit an adaptive immune response against tumours and pathogens. And it occurs through multiple pathways...

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Bibliographic Details
Main Authors: Yi-Rao Zhou, Jun-Jie Dang, Qi-Chao Yang, Zhi-Jun Sun
Format: Article
Language:English
Published: Elsevier 2024-11-01
Series:EBioMedicine
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Online Access:http://www.sciencedirect.com/science/article/pii/S2352396424004560
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