Handgrip strength, cardiometabolic risk and body composition in youth with type 1 diabetes: the Diactive-1 Cohort Study
Objective This study aimed to explore the association between handgrip strength, cardiometabolic risk (CMR) and body composition in youth with type 1 diabetes.Methods For this prospective cohort study, muscular fitness was assessed via handgrip test and relativised by weight, and body composition, e...
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| Language: | English |
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BMJ Publishing Group
2024-12-01
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| Series: | BMJ Open Sport & Exercise Medicine |
| Online Access: | https://bmjopensem.bmj.com/content/10/4/e002177.full |
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| author | Antonio García-Hermoso Mikel Izquierdo Yasmin Ezzatvar Nidia Huerta-Uribe Ignacio Hormazábal-Aguayo Jacinto Muñoz-Pardeza María J Chueca-Guindulain Sara Berrade-Zubiri Carlos Andrés Sesma Elisabet Burillo Sánchez Rodrigo Yáñez-Sepúlveda |
| author_facet | Antonio García-Hermoso Mikel Izquierdo Yasmin Ezzatvar Nidia Huerta-Uribe Ignacio Hormazábal-Aguayo Jacinto Muñoz-Pardeza María J Chueca-Guindulain Sara Berrade-Zubiri Carlos Andrés Sesma Elisabet Burillo Sánchez Rodrigo Yáñez-Sepúlveda |
| author_sort | Antonio García-Hermoso |
| collection | DOAJ |
| description | Objective This study aimed to explore the association between handgrip strength, cardiometabolic risk (CMR) and body composition in youth with type 1 diabetes.Methods For this prospective cohort study, muscular fitness was assessed via handgrip test and relativised by weight, and body composition, evaluated through dual-energy X-ray absorptiometry in type 1 diabetes patients aged 6–18 years. CMR score included z-scores for total body fat, blood pressure, glycated haemoglobin (HbA1c), low-density lipoprotein cholesterol, high-density lipoprotein cholesterol and triglyceride-glucose index.Results Eighty-three patients were analysed at baseline and 1-year follow-up (44.6% females, mean age 12.77 years). Individuals with high handgrip strength tended to have lower CMR and body fat compared with those with low handgrip strength. Over a year, individuals with high handgrip strength showed reduced HbA1c, CMR and subcutaneous fat. Consistently meeting high handgrip strength criteria resulted in reductions in HbA1c levels, CMR score and subcutaneous adipose tissue compared with those who never complied or lost compliance during follow-up. Additionally, subjects classified with high handgrip strength both at baseline and follow-up had a lower likelihood of being classified with high CMR (OR=0.241, 95% CI 0.121 to 0.947, p=0.044).Conclusions High handgrip strength was associated with significant cardiometabolic and body composition benefits in youth with type 1 diabetes. This tool could be considered of potential clinical value for incorporating assessments like handgrip tests to monitor and address cardiometabolic health. |
| format | Article |
| id | doaj-art-73a96cc7159d4e678aabbbd84a1cb4b9 |
| institution | Kabale University |
| issn | 2055-7647 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Open Sport & Exercise Medicine |
| spelling | doaj-art-73a96cc7159d4e678aabbbd84a1cb4b92024-12-16T15:55:13ZengBMJ Publishing GroupBMJ Open Sport & Exercise Medicine2055-76472024-12-0110410.1136/bmjsem-2024-002177Handgrip strength, cardiometabolic risk and body composition in youth with type 1 diabetes: the Diactive-1 Cohort StudyAntonio García-Hermoso0Mikel Izquierdo1Yasmin Ezzatvar2Nidia Huerta-Uribe3Ignacio Hormazábal-Aguayo4Jacinto Muñoz-Pardeza5María J Chueca-Guindulain6Sara Berrade-Zubiri7Carlos Andrés Sesma8Elisabet Burillo Sánchez9Rodrigo Yáñez-Sepúlveda102 Universidad Pública de Navarra, Pamplona, Navarra, Spain1 Navarrabiomed, Hospital Universitario de Navarra (HUN)-Universidad Pública de Navarra (UPNA), IdiSNA, Pamplona, SpainLifestyle Factors with Impact on Ageing and Overall Health (LAH) Research Group, Nursing Department, Universitat de València, Valencia, SpainNavarrabiomed, Hospital Universitario de Navarra, IdiSNA, Universidad Pública de Navarra, Pamplona, SpainNavarrabiomed, Hospital Universitario de Navarra, IdiSNA, Universidad Pública de Navarra, Pamplona, SpainNavarrabiomed, Hospital Universitario de Navarra, IdiSNA, Universidad Pública de Navarra, Pamplona, SpainPediatric Endocrinology Unit, Department of Pediatrics, IdiSNA, Hospital Universitario de Navarra, Pamplona, SpainPediatric Endocrinology Unit, Department of Pediatrics, IdiSNA, Hospital Universitario de Navarra, Pamplona, SpainPediatric Endocrinology Unit, Department of Pediatrics, IdiSNA, Hospital Universitario de Navarra, Pamplona, SpainPediatric Endocrinology Unit, Department of Pediatrics, IdiSNA, Hospital Universitario de Navarra, Pamplona, SpainFaculty of Education and Social Sciences, Universidad Andrés Bello, Viña del Mar, ChileObjective This study aimed to explore the association between handgrip strength, cardiometabolic risk (CMR) and body composition in youth with type 1 diabetes.Methods For this prospective cohort study, muscular fitness was assessed via handgrip test and relativised by weight, and body composition, evaluated through dual-energy X-ray absorptiometry in type 1 diabetes patients aged 6–18 years. CMR score included z-scores for total body fat, blood pressure, glycated haemoglobin (HbA1c), low-density lipoprotein cholesterol, high-density lipoprotein cholesterol and triglyceride-glucose index.Results Eighty-three patients were analysed at baseline and 1-year follow-up (44.6% females, mean age 12.77 years). Individuals with high handgrip strength tended to have lower CMR and body fat compared with those with low handgrip strength. Over a year, individuals with high handgrip strength showed reduced HbA1c, CMR and subcutaneous fat. Consistently meeting high handgrip strength criteria resulted in reductions in HbA1c levels, CMR score and subcutaneous adipose tissue compared with those who never complied or lost compliance during follow-up. Additionally, subjects classified with high handgrip strength both at baseline and follow-up had a lower likelihood of being classified with high CMR (OR=0.241, 95% CI 0.121 to 0.947, p=0.044).Conclusions High handgrip strength was associated with significant cardiometabolic and body composition benefits in youth with type 1 diabetes. This tool could be considered of potential clinical value for incorporating assessments like handgrip tests to monitor and address cardiometabolic health.https://bmjopensem.bmj.com/content/10/4/e002177.full |
| spellingShingle | Antonio García-Hermoso Mikel Izquierdo Yasmin Ezzatvar Nidia Huerta-Uribe Ignacio Hormazábal-Aguayo Jacinto Muñoz-Pardeza María J Chueca-Guindulain Sara Berrade-Zubiri Carlos Andrés Sesma Elisabet Burillo Sánchez Rodrigo Yáñez-Sepúlveda Handgrip strength, cardiometabolic risk and body composition in youth with type 1 diabetes: the Diactive-1 Cohort Study BMJ Open Sport & Exercise Medicine |
| title | Handgrip strength, cardiometabolic risk and body composition in youth with type 1 diabetes: the Diactive-1 Cohort Study |
| title_full | Handgrip strength, cardiometabolic risk and body composition in youth with type 1 diabetes: the Diactive-1 Cohort Study |
| title_fullStr | Handgrip strength, cardiometabolic risk and body composition in youth with type 1 diabetes: the Diactive-1 Cohort Study |
| title_full_unstemmed | Handgrip strength, cardiometabolic risk and body composition in youth with type 1 diabetes: the Diactive-1 Cohort Study |
| title_short | Handgrip strength, cardiometabolic risk and body composition in youth with type 1 diabetes: the Diactive-1 Cohort Study |
| title_sort | handgrip strength cardiometabolic risk and body composition in youth with type 1 diabetes the diactive 1 cohort study |
| url | https://bmjopensem.bmj.com/content/10/4/e002177.full |
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