Pimozide Inhibits Type II but Not Type I Hair Cells in Chicken Embryo and Adult Mouse Vestibular Organs

Pimozide Inhibits Type II but Not Type I Hair Cells in Chicken Embryo and Adult Mouse Vestibular Organs

Background: Pimozide is a conventional antipsychotic drug of the diphenylbutylpiperidine class, widely used for treating schizophrenia and delusional disorders and for managing motor and phonic tics in Tourette’s syndrome. Pimozide is known to block dopaminergic D2 receptors and various types of vol...

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Bibliographic Details
Main Authors: Roberta Giunta, Giulia Cheli, Giorgio Rispoli, Giancarlo Russo, Sergio Masetto
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Biomedicines
Subjects:
pimozide
antipsychotic drug
hair cell
vestibular
patch clamp
ionic currents
Online Access:https://www.mdpi.com/2227-9059/12/12/2879
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