Evaluation of the Clinical Outcomes of Regenerative Endodontic Procedures Using Autologous Platelet Concentrate: A Systematic Review and Meta-Analysis
Objective: To assess the clinical outcomes of regenerative endodontic procedures using autologous platelet concentrate. Both regeneration and apexification procedures were examined and compared with each other. Material and Methods: The PRISMA 2020 Checklist has been utilized to carry out the system...
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| Format: | Article |
| Language: | English |
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Association of Support to Oral Health Research (APESB)
2024-11-01
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| Series: | Pesquisa Brasileira em Odontopediatria e Clínica Integrada |
| Subjects: | |
| Online Access: | https://revista.uepb.edu.br/PBOCI/article/view/3900 |
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| _version_ | 1846172671508742144 |
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| author | Elnaz Mousavi Navid Nasrabadi Samira Jamali Arian Haddadi |
| author_facet | Elnaz Mousavi Navid Nasrabadi Samira Jamali Arian Haddadi |
| author_sort | Elnaz Mousavi |
| collection | DOAJ |
| description | Objective: To assess the clinical outcomes of regenerative endodontic procedures using autologous platelet concentrate. Both regeneration and apexification procedures were examined and compared with each other. Material and Methods: The PRISMA 2020 Checklist has been utilized to carry out the systematic review and meta-analysis for the present study. PubMed, Scopus, Web of Science, EBSCO, Embase, and ISI Web of Knowledge have been reviewed for systematic literature until May 2023. A fixed-effect model and a Mantel-Haenszel methodology have been used to measure the risk ratio's 95% confidence interval. Then, Meta-analyses were carried out utilizing Stata/MP version 17. Results: Duplicate studies were eliminated from the first review, 849 studies' abstracts were reviewed, two authors reviewed 103 papers' full texts, and finally, 20 articles were selected. The survival rate in regenerative endodontic procedures between apexification and regenerative endodontic procedures was -0.01 (RR: -0.01, 95% CI: -0.05, 0.02; p=0.35). Conclusion: Throughout the present meta-analysis, regenerative endodontic therapy is an effective intervention with a high survival and success rate in managing immature necrotic permanent teeth. |
| format | Article |
| id | doaj-art-736fbbbcfa544cf081cc8c93d6ea5951 |
| institution | Kabale University |
| issn | 1519-0501 1983-4632 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Association of Support to Oral Health Research (APESB) |
| record_format | Article |
| series | Pesquisa Brasileira em Odontopediatria e Clínica Integrada |
| spelling | doaj-art-736fbbbcfa544cf081cc8c93d6ea59512024-11-09T13:14:30ZengAssociation of Support to Oral Health Research (APESB)Pesquisa Brasileira em Odontopediatria e Clínica Integrada1519-05011983-46322024-11-0125Evaluation of the Clinical Outcomes of Regenerative Endodontic Procedures Using Autologous Platelet Concentrate: A Systematic Review and Meta-AnalysisElnaz MousaviNavid NasrabadiSamira JamaliArian HaddadiObjective: To assess the clinical outcomes of regenerative endodontic procedures using autologous platelet concentrate. Both regeneration and apexification procedures were examined and compared with each other. Material and Methods: The PRISMA 2020 Checklist has been utilized to carry out the systematic review and meta-analysis for the present study. PubMed, Scopus, Web of Science, EBSCO, Embase, and ISI Web of Knowledge have been reviewed for systematic literature until May 2023. A fixed-effect model and a Mantel-Haenszel methodology have been used to measure the risk ratio's 95% confidence interval. Then, Meta-analyses were carried out utilizing Stata/MP version 17. Results: Duplicate studies were eliminated from the first review, 849 studies' abstracts were reviewed, two authors reviewed 103 papers' full texts, and finally, 20 articles were selected. The survival rate in regenerative endodontic procedures between apexification and regenerative endodontic procedures was -0.01 (RR: -0.01, 95% CI: -0.05, 0.02; p=0.35). Conclusion: Throughout the present meta-analysis, regenerative endodontic therapy is an effective intervention with a high survival and success rate in managing immature necrotic permanent teeth.https://revista.uepb.edu.br/PBOCI/article/view/3900AutograftsRegenerative EndodonticsRoot Canal ObturationThrombosis |
| spellingShingle | Elnaz Mousavi Navid Nasrabadi Samira Jamali Arian Haddadi Evaluation of the Clinical Outcomes of Regenerative Endodontic Procedures Using Autologous Platelet Concentrate: A Systematic Review and Meta-Analysis Pesquisa Brasileira em Odontopediatria e Clínica Integrada Autografts Regenerative Endodontics Root Canal Obturation Thrombosis |
| title | Evaluation of the Clinical Outcomes of Regenerative Endodontic Procedures Using Autologous Platelet Concentrate: A Systematic Review and Meta-Analysis |
| title_full | Evaluation of the Clinical Outcomes of Regenerative Endodontic Procedures Using Autologous Platelet Concentrate: A Systematic Review and Meta-Analysis |
| title_fullStr | Evaluation of the Clinical Outcomes of Regenerative Endodontic Procedures Using Autologous Platelet Concentrate: A Systematic Review and Meta-Analysis |
| title_full_unstemmed | Evaluation of the Clinical Outcomes of Regenerative Endodontic Procedures Using Autologous Platelet Concentrate: A Systematic Review and Meta-Analysis |
| title_short | Evaluation of the Clinical Outcomes of Regenerative Endodontic Procedures Using Autologous Platelet Concentrate: A Systematic Review and Meta-Analysis |
| title_sort | evaluation of the clinical outcomes of regenerative endodontic procedures using autologous platelet concentrate a systematic review and meta analysis |
| topic | Autografts Regenerative Endodontics Root Canal Obturation Thrombosis |
| url | https://revista.uepb.edu.br/PBOCI/article/view/3900 |
| work_keys_str_mv | AT elnazmousavi evaluationoftheclinicaloutcomesofregenerativeendodonticproceduresusingautologousplateletconcentrateasystematicreviewandmetaanalysis AT navidnasrabadi evaluationoftheclinicaloutcomesofregenerativeendodonticproceduresusingautologousplateletconcentrateasystematicreviewandmetaanalysis AT samirajamali evaluationoftheclinicaloutcomesofregenerativeendodonticproceduresusingautologousplateletconcentrateasystematicreviewandmetaanalysis AT arianhaddadi evaluationoftheclinicaloutcomesofregenerativeendodonticproceduresusingautologousplateletconcentrateasystematicreviewandmetaanalysis |