Atrophy of hypothalamic subregions increases migraine risk: cross-sectional study and mendelian randomization analysis

Atrophy of hypothalamic subregions increases migraine risk: cross-sectional study and mendelian randomization analysis

Abstract Background The hypothalamus is a versatile structure comprising several nuclei that play key roles in regulating various biological processes associated with migraine, including hormone secretion, metabolism, circadian rhythm, and autonomic nervous system functions. However, the involvement...

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Main Authors: Zhonghua Xiong, Lei Zhao, Geyu Liu, Dong Qiu, Yanliang Mei, Xiaoshuang Li, Zhi Guo, Peng Zhang, Mantian Zhang, Tianshuang Gao, Jinju Sun, Xin Liu, Yonggang Wang
Format: Article
Language:English
Published: BMC 2025-08-01
Series:The Journal of Headache and Pain
Subjects:
Migraine
Hypothalamus subregions
Gut Microbiome
MRI
Mendelian randomization
Online Access:https://doi.org/10.1186/s10194-025-02119-8
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