Normal development of mice lacking PAXX, the paralogue of XRCC4 and XLF

DNA repair consists of several cellular pathways which recognize and repair damaged DNA. The classical nonhomologous DNA end‐joining (NHEJ) pathway repairs double‐strand breaks in DNA. It is required for maturation of both B and T lymphocytes by supporting V(D)J recombination as well as B‐cell diffe...

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Bibliographic Details
Main Authors: Raquel Gago‐Fuentes, Mengtan Xing, Siri Sæterstad, Antonio Sarno, Alisa Dewan, Carole Beck, Stefano Bradamante, Magnar Bjørås, Valentyn Oksenych
Format: Article
Language:English
Published: Wiley 2018-03-01
Series:FEBS Open Bio
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Online Access:https://doi.org/10.1002/2211-5463.12381
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