Luliconazole-loaded nanostructured lipid carrier: formulation, characterization, and in vitro antifungal evaluation against a panel of resistant fungal strains

Abstract Luliconazole (LCZ) is a topical imidazole antifungal agent with broad-spectrum activity. However, LCZ encounters challenges such as low aqueous solubility, skin retention, and penetration, which reduce its dermal bioavailability and hinder its efficacy in drug delivery. The aim of the prese...

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Bibliographic Details
Main Authors: Mohsen Nosratabadi, Seyyed Mobin Rahimnia, Robab Ebrahimi Barogh, Mahdi Abastabar, Iman Haghani, Javad Akhtari, Zohreh Hajheydari, Pedram Ebrahimnejad
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-024-79225-1
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