Vacuolar ATPase as a potential therapeutic target and mediator of treatment resistance in cancer

Abstract Vacuolar ATPase (V‐ATPase) is an ATP‐dependent H+‐transporter that pumps protons across intracellular and plasma membranes. It consists of a large multi‐subunit protein complex and influences a wide range of cellular processes. This review focuses on emerging evidence for the roles for V‐AT...

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Bibliographic Details
Main Authors: Bradleigh Whitton, Haruko Okamoto, Graham Packham, Simon J. Crabb
Format: Article
Language:English
Published: Wiley 2018-08-01
Series:Cancer Medicine
Subjects:
Online Access:https://doi.org/10.1002/cam4.1594
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