Activation of LXR signaling ameliorates apoptosis of alveolar epithelial cells in Bronchopulmonary dysplasia

Activation of LXR signaling ameliorates apoptosis of alveolar epithelial cells in Bronchopulmonary dysplasia

Abstract Background and purposes Liver X receptors (LXRs) are specialized nuclear receptors essential for maintaining cholesterol homeostasis, modulating LXR activity could have therapeutic potential in lung diseases. Bronchopulmonary dysplasia (BPD) is a chronic lung disease characterized by impair...

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Bibliographic Details
Main Authors: Yizhe Ma, Yameng Wang, Anni Xie, Luchun Wang, Yuqiong Zhang, Mingyan Tao, Xianhui Deng, Zhidan Bao, Renqiang Yu
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Respiratory Research
Subjects:
Bronchopulmonary dysplasia
Apoptosis
Alveolar epithelial cells
LXR
Cholesterol homeostasis
Online Access:https://doi.org/10.1186/s12931-024-03031-6
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