Molecular characteristics of NPM1 mutations in AML patients using targeted NGS
Background Acute myeloid leukemia (AML) is a clonal hematopoietic stem cell malignancy characterized by the accumulation of myeloid progenitor cells with arrested differentiation, leading to the suppression of normal hematopoiesis. The disease exhibits significant heterogeneity, with less than 30% f...
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Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2024-12-01
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Series: | Alexandria Journal of Medicine |
Subjects: | |
Online Access: | https://www.tandfonline.com/doi/10.1080/20905068.2024.2395583 |
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