Endogenous ZAP is associated with altered Zika virus infection phenotype

Abstract The zinc finger antiviral protein 1 (ZAP) has broad antiviral activity. ZAP is an interferon (IFN)-stimulated gene, which itself may enhance type I IFN antiviral response. In a previous study, Zika virus was identified as ZAP-resistant and not sensitive to ZAP antiviral activity. Here, we f...

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Bibliographic Details
Main Authors: Nguyen Phuong Khanh Le, Prince Pal Singh, Ahmad Jawad Sabir, Ivan Trus, Uladzimir Karniychuk
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Virology Journal
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Online Access:https://doi.org/10.1186/s12985-024-02557-x
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