Modulators of Alpha-2 Macroglobulin Upregulation by High Glucose in Glomerular Mesangial Cells

Up to 40% of patients with diabetes mellitus will develop diabetic kidney disease (DKD), characterized pathologically by the accumulation of extracellular matrix proteins, which leads to the loss of kidney function over time. Our previous studies showed that the pan-protease inhibitor alpha 2-macrog...

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Bibliographic Details
Main Authors: Jackie Trink, Renzhong Li, Bo Gao, Chao Lu, Joan C. Krepinsky
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/14/11/1444
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