Cheminformatics-based design and biomedical applications of a new Hydroxyphenylcalix[4] resorcinarene as anti-cancer agent

Cheminformatics-based design and biomedical applications of a new Hydroxyphenylcalix[4] resorcinarene as anti-cancer agent

Abstract The distinct conformational characteristics, functionality, affordability, low toxicity, and usefulness make calixarene-based compounds a promising treatment option for cancer. The aim of the present study is to synthesize a new calixarene-based compound and assess of its anticancer potenti...

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Main Authors: S. F. Alshahateet, R. M. Altarawneh, S. A. Al-Trawneh, Y. M. Al-Saraireh, W. M. Al-Tawarh, K. R. Abuawad, Y. M. Abuhalaweh, M. Zerrouk, A. Ait Mansour, R. Salghi, B. Hammouti, M. Merzouki, R. Sabbahi, L. Rhazi, Mohammed M. Alanazi, K. Azzaoui
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Scientific Reports
Subjects:
Anti-cancer agent
Calix[n]arenes
MTT assay
Anti-proliferative activity
Molecular docking
Online Access:https://doi.org/10.1038/s41598-024-82115-1
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https://doi.org/10.1038/s41598-024-82115-1

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