DNA methylation-based telomere length is more strongly associated with cardiovascular disease and long-term mortality than quantitative polymerase chain reaction-based telomere length: evidence from the NHANES 1999–2002

DNA methylation-based telomere length is more strongly associated with cardiovascular disease and long-term mortality than quantitative polymerase chain reaction-based telomere length: evidence from the NHANES 1999–2002

Abstract Background Telomere length (TL) serves as a pivotal gauge of cellular aging, with shorter TL linked to various age-related ailments. Recently, a DNA methylation-based TL estimator, known as DNAmTL, has emerged as a novel TL measurement tool. Our current investigation scrutinized the correla...

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Bibliographic Details
Main Authors: Qianhui Wang, Yuanfeng Gao, Jie Song, Dilare Taiwaikuli, Huanhuan Ding, Xinchun Yang, Baopeng Tang, Xianhui Zhou
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Clinical Epigenetics
Subjects:
DNA methylation
Telomere length
Cardiovascular disease
Mortality
NHANES
Aging
Online Access:https://doi.org/10.1186/s13148-024-01795-8
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https://doi.org/10.1186/s13148-024-01795-8

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