Transcriptome-based characterization of 3’2’-cGAMP signaling mediated immune responses

Transcriptome-based characterization of 3’2’-cGAMP signaling mediated immune responses

Cyclic dinucleotides (CDNs) are critical adjuvants in antiviral vaccines and cancer immunotherapy, primarily through the activation of the cGAS-STING signaling pathway. Evaluating the immune responses triggered by CDNs is essential for the development of effective adjuvants. In this study, we perfor...

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Bibliographic Details
Main Authors: Yan Gao, Gucheng Xu, Munire Maimaiti, Saihua Chen, Xiang Zhang, Jiameng Hu, Chen Wang, Ze Hong, Haiyang Hu
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Computational and Structural Biotechnology Journal
Subjects:
3’2’-cGAMP signaling
2’3’-cGAMP signaling
STING
Transcriptome
Adjuvant
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037024003921
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