Gut microbiota-regulated unconjugated bilirubin metabolism drives renal calcium oxalate crystal deposition

Gut microbiota-regulated unconjugated bilirubin metabolism drives renal calcium oxalate crystal deposition

Gut microbial dysbiosis and the resultant metabolic disorder are intimately associated with calcium oxalate (CaOx) stone formation. Renal CaOx crystal deposition is one of the primary initiating factors of CaOx formation; however, the critical signaling metabolites communicating along the gut–kidney...

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Main Authors: Shujue Li, Wenzheng Wu, Yuhao Zhou, Shike Zhang, Daqiang Wei, Mingzhao Zhu, Xiaoling Ying, Xinyuan Sun, Hongxing Liu, Wei Zhu, Daolin Tang, Renjie Jiao, Guohua Zeng, Xiaolu Duan, Jinbao Liu, Wenqi Wu
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Gut Microbes
Subjects:
CaOx crystal deposition
gut microbiota
unconjugated bilirubin
oxalate secretion
Online Access:https://www.tandfonline.com/doi/10.1080/19490976.2025.2546158
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https://www.tandfonline.com/doi/10.1080/19490976.2025.2546158

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