Sparstolonin B potentiates the antitumor activity of nanovesicle-loaded drugs by suppressing the phagocytosis of macrophages in vivo

Sparstolonin B potentiates the antitumor activity of nanovesicle-loaded drugs by suppressing the phagocytosis of macrophages in vivo

Abstract Background Extracellular vesicles (EVs) and extruded nanovesicles (ENVs) are promising nanovesicles (NVs) for drug delivery. However, the application of these NVs is strongly hindered by their short half-life in the circulation. Macrophages (Mφs) in the liver and spleen contribute to the ra...

Full description

Saved in:
Bibliographic Details
Main Authors: Yuefeng Zhang, Zuo Mou, Wei Song, Xiaoqin He, Qin Yi, Zhekai Wang, Xietong Mao, Wei Wang, Yangtao Xu, Yang Shen, Peng Ma, Kaihuan Yu
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Journal of Nanobiotechnology
Subjects:
Nanovesicles
Macrophages
Phagocytosis
Toll-like receptor 2
Drug delivery
Online Access:https://doi.org/10.1186/s12951-024-03001-6
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1186/s12951-024-03001-6

Similar Items