Selenium nanoparticles modified niobium MXene for non-enzymatic detection of glucose

Abstract Glucose sensing remains a crucial need as diabetes is a worldwide concern. This work reports the application of Nb2CT x —selenium nanoparticle composite material for the nonenzymatic sensing of glucose. The surface morphology of the synthesized composite was analyzed using various microscop...

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Main Authors: Prabisha K. E., Neena P. K., Menon Ankitha, P. Abdul Rasheed, P. V. Suneesh, T. G. Satheesh Babu
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-85748-y
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Summary:Abstract Glucose sensing remains a crucial need as diabetes is a worldwide concern. This work reports the application of Nb2CT x —selenium nanoparticle composite material for the nonenzymatic sensing of glucose. The surface morphology of the synthesized composite was analyzed using various microscopic techniques like scanning electron microscopy, transmission electron microscopy, and its structural properties were analyzed using diffraction and spectroscopic methods. A gold disc electrode was modified using the nanocomposite and tested for glucose in an alkaline medium. The sensing was based on the oxidation of glucose on the catalytic surface. The glucose was quantified amperometrically at a significantly lower overpotential of 0.16 V. The sensor showed a good detection range from 2 to 30 mM with a sensitivity of 4.15 µA mM−1 cm−2 and a detection limit of 1.1 mM.
ISSN:2045-2322